Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275658 | 0.86 | GAA (0.42) | GAAITGB3ITGA2BBRD4MIF | |
| SCHEMBL7275480 | 0.79 | GAA (0.37) | GAAITGB3ITGA2BBRD4HTT | |
| Hydrochloric Acid SCHEMBL7281221 | 0.74 | ITGB3 (0.57) | ITGB3ITGA2BIRAK4KDM4E | |
| SCHEMBL5533516 | 0.73 | GAA (0.33) | GAAITGB3ITGA2BIRAK4 | |
| SCHEMBL5533509 | 0.73 | GAA (0.33) | GAAITGB3ITGA2BIRAK4 | |
| SCHEMBL5533521 | 0.73 | GAA (0.33) | GAAITGB3ITGA2BIRAK4 | |
| Hydrochloric Acid SCHEMBL7274849 | 0.72 | ITGB3 (0.55) | ITGB3ITGA2BIRAK4KDM4E | |
| SCHEMBL7283083 | 0.70 | ITGB3 (0.56) | ITGB3ITGA2BKMT2AIRAK4KDM4E | |
| SCHEMBL7282562 | 0.70 | ITGB3 (0.56) | ITGB3ITGA2BKMT2AIRAK4KDM4E | |
| SCHEMBL7283424 | 0.70 | TDP1 (0.36) | GAAITGB3ITGA2BL3MBTL1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528369-B1 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | BOEHRINGER INGELHEIM PHARMA (DE) | 1999-11-24 | — | — | EP | disclosed |
| US-5455348-A | Anticoagulants | Thomae, Karl (DE) | 1995-10-03 | — | — | US | disclosed |
| EP-0528369-A2 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-02-24 | — | — | EP | disclosed |