Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3358349 | 0.84 | SIGMAR1 (0.54) | — | |
| SCHEMBL4258936 | 0.80 | KDM4E (0.44) | — | |
| SCHEMBL3090521 | 0.76 | FAAH (0.50) | FAAH | |
| SCHEMBL10642932 | 0.75 | TAAR1 (0.45) | TAAR1CYP19A1 | |
| SCHEMBL7103234 | 0.71 | SLC18A3 (0.62) | — | |
| SCHEMBL31490479 | 0.70 | SLC18A3 (0.57) | — | |
| SCHEMBL7419921 | 0.69 | SLC18A3 (0.60) | — | |
| Ammonia Solution, Strong SCHEMBL20702116 | 0.69 | SLC18A3 (0.56) | — | |
| SCHEMBL2440428 | 0.69 | SLC18A3 (0.60) | — | |
| SCHEMBL9133642 | 0.69 | SLC18A3 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839798-A2 | Intermediates for preparating non-peptide retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1998-05-06 | — | — | EP | disclosed |
| US-5670675-A | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1997-09-23 | — | — | US | disclosed |
| US-5545750-A | TREATING HUMAN IMMUNODEFICIENCY VIRUS | ABBOTT LABORATORIES (US) | 1996-08-13 | — | — | US | disclosed |
| US-5248677-A | Nervous system disorders or antidepressants | ABBOTT LABORATORIES (US) | 1993-09-28 | — | — | US | disclosed |
| US-5180733-A | Antidepressants or nervous systen disorders | ABBOTT LABORATORIES (US) | 1993-01-19 | — | — | US | disclosed |
| US-5142056-A | Human immunodeficiency virus protease inhibitor | ABBOTT LABORATORIES (US) | 1992-08-25 | — | — | US | disclosed |
| EP-0461353-A1 | Biogenic amine uptake inhibitors | ABBOTT LABORATORIES (US) | 1991-12-18 | — | — | EP | disclosed |
| EP-0402646-A1 | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1990-12-19 | — | — | EP | disclosed |