Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.40 |
| ▸ | ADK | P55263 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7291584 | 0.99 | CMA1 (0.40) | CMA1CHRM1MEN1KMT2AGSK3B | |
| SCHEMBL7291570 | 0.92 | CMA1 (0.41) | CMA1GSK3BALDH1A1ADKGSK3A | |
| SCHEMBL7287822 | 0.88 | TSHR (0.44) | MEN1KMT2AGSK3BALDH1A1NPSR1 | |
| SCHEMBL7288360 | 0.88 | MEN1 (0.46) | MEN1KMT2AALDH1A1POLBCA9 | |
| SCHEMBL7287042 | 0.87 | MEN1 (0.44) | MEN1KMT2AGSK3BALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL7287352 | 0.87 | TSHR (0.43) | MEN1KMT2AGSK3BALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL7288500 | 0.86 | MEN1 (0.43) | MEN1KMT2AGSK3BALDH1A1POLB | |
| SCHEMBL7288382 | 0.81 | TSHR (0.39) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL7287310 | 0.80 | TSHR (0.46) | POLBNPSR1CA12CA1CA2 | |
| SCHEMBL7287339 | 0.80 | TSHR (0.44) | MEN1KMT2AGSK3BALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313393-B1 | Benzoxazine compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4892872-A | ANTIEMETICS, ANTINAUSEA | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0313393-A2 | Benzoxazine compounds and pharmaceutical use thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-04-26 | — | — | EP | disclosed |