Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MYC | P01106 | 2/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288360 | 0.85 | MEN1 (0.46) | TSHRALDH1A1L3MBTL1POLBMEN1 | |
| SCHEMBL7287822 | 0.83 | TSHR (0.44) | TSHRHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL7282398 | 0.83 | HTR2A (0.36) | TSHRHSD17B10ALOX15ALDH1A1DYRK1A | |
| SCHEMBL7278698 | 0.83 | ALDH1A1 (0.45) | TSHRALDH1A1L3MBTL1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7287352 | 0.83 | TSHR (0.43) | TSHRHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL7287042 | 0.83 | MEN1 (0.44) | TSHRALDH1A1POLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7288578 | 0.82 | ALDH1A1 (0.44) | TSHRALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL7287310 | 0.82 | TSHR (0.46) | TSHRHSD17B10ALOX15POLBHTT | |
| Hydrochloric Acid SCHEMBL7288500 | 0.82 | MEN1 (0.43) | TSHRALDH1A1POLBMEN1KMT2A | |
| SCHEMBL7278129 | 0.81 | CMA1 (0.41) | ALDH1A1POLBMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313393-B1 | Benzoxazine compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4892872-A | ANTIEMETICS, ANTINAUSEA | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0313393-A2 | Benzoxazine compounds and pharmaceutical use thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-04-26 | — | — | EP | disclosed |