Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | MITF | O75030 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.54 |
| ▸ | HTR3B | O95264 | 1/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.54 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | STAT6 | P42226 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodomethane SCHEMBL7279016 | 0.97 | ALDH1A1 (0.61) | ALDH1A1LMNAMITFMAPTKMT2A | |
| SCHEMBL27249799 | 0.85 | LMNA (0.68) | ALDH1A1LMNAMITFMAPTKMT2A | |
| SCHEMBL14745414 | 0.84 | LMNA (0.71) | ALDH1A1LMNAMITFMAPTKMT2A | |
| SCHEMBL7278079 | 0.83 | LMNA (0.43) | ALDH1A1LMNAMITFMAPTKMT2A | |
| SCHEMBL11227116 | 0.82 | LMNA (0.68) | ALDH1A1LMNAMITFMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL7278455 | 0.82 | LMNA (0.43) | ALDH1A1LMNAMITFMAPTKMT2A | |
| SCHEMBL27249475 | 0.81 | LMNA (0.55) | ALDH1A1LMNAMITFMAPTKMT2A | |
| SCHEMBL7278172 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNAMITFMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL7278265 | 0.80 | ALDH1A1 (0.45) | ALDH1A1LMNAMITFMAPTKMT2A | |
| SCHEMBL4106159 | 0.80 | KMT2A (0.73) | ALDH1A1LMNAMITFMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814344-A | ANTIEMENTICS, ANTIPSYCHOTICS | GLAXO GROUP LIMITED | 1989-03-21 | — | — | US | disclosed |
| EP-0266899-A2 | Indole derivatives | GLAXO GROUP LIMITED (GB) | 1988-05-11 | — | — | EP | disclosed |