Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9238889 | 0.83 | KMT2A (0.34) | KMT2AALDH1A1 | |
| SCHEMBL9238883 | 0.83 | KMT2A (0.34) | KMT2AALDH1A1 | |
| SCHEMBL7278738 | 0.74 | KMT2A (0.35) | KMT2AALDH1A1 | |
| SCHEMBL7278732 | 0.74 | KMT2A (0.35) | KMT2AALDH1A1 | |
| SCHEMBL9848597 | 0.72 | KMT2A (0.38) | KMT2AALDH1A1KDM4E | |
| SCHEMBL9848598 | 0.72 | KMT2A (0.38) | KMT2AALDH1A1KDM4E | |
| SCHEMBL7271334 | 0.68 | KMT2A (0.32) | KMT2AALDH1A1KDM4E | |
| SCHEMBL8765130 | 0.66 | MEN1 (0.40) | KMT2AALDH1A1 | |
| SCHEMBL9848559 | 0.66 | KMT2A (0.42) | KMT2AALDH1A1KDM4E | |
| SCHEMBL8765133 | 0.66 | MEN1 (0.40) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679645-A1 | Pharmacologically active CNS pyridmidin compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-11-02 | — | — | EP | disclosed |
| EP-0459819-A2 | Pharmacologically active CNS compound | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |