Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 3/20 | 0.56 |
| ▸ | GABRD | O14764 | 3/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.56 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.56 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.56 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.56 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.56 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.56 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.56 |
| ▸ | GABRE | P78334 | 3/20 | 0.56 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.56 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.56 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.56 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.56 |
| ▸ | BRS3 | P32247 | 9/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.38 |
| ▸ | KDM6B | O15054 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7286265 | 0.74 | GABRP (0.70) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7279224 | 0.69 | GABRP (0.63) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4633468 | 0.69 | GABRP (0.62) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL14199723 | 0.66 | GABRP (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11703415 | 0.66 | GABRP (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30740846 | 0.65 | P4HA1 (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29403841 | 0.65 | NOTUM (0.32) | ALDH1A1 | |
| SCHEMBL11079329 | 0.65 | GABRP (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL13611417 | 0.65 | GABRP (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6962603 | 0.64 | NR1H2 (0.36) | CYP3A4MAPTAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904675-A | Phamacologically active 5-carboxy-2-(5-tetrazolyl) pyridines | ZYMA SA (CH) | 1990-02-27 | — | — | US | disclosed |
| EP-0278908-A2 | Heterocyclic compounds | Zyma SA (CH) | 1988-08-17 | — | — | EP | disclosed |