Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL728780 | 0.89 | DPP7 (0.45) | DPP7L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL4639703 | 0.87 | DPP7 (0.46) | DPP7L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL18395081 | 0.83 | L3MBTL1 (0.54) | DPP7L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL10710452 | 0.76 | GAA (0.44) | DPP7L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL13724662 | 0.74 | HPGD (0.49) | L3MBTL1MEN1KMT2AALDH1A1HTT | |
| SCHEMBL15068892 | 0.74 | HPGD (0.49) | L3MBTL1MEN1KMT2AALDH1A1HTT | |
| SCHEMBL1291922 | 0.72 | KMT2A (0.35) | MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL16574601 | 0.71 | DPP7 (0.45) | DPP7L3MBTL1MMP1MMP2MMP8 | |
| SCHEMBL9853145 | 0.70 | KMT2A (0.39) | MEN1KMT2AALDH1A1 | |
| SCHEMBL1160173 | 0.70 | KMT2A (0.39) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011529986-A | — | — | 2011-12-15 | — | — | JP | claimed |
| EP-2307480-A1 | HEAT RESISTANT THERMOPLASTIC ARTICLES INCLUDING CO-STABILIZERS | E. I. du Pont de Nemours and Company (US) | 2011-04-13 | — | — | EP | claimed |
| WO-2010014785-A1 | HEAT RESISTANT THERMOPLASTIC ARTICLES INCLUDING CO-STABILIZERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-02-04 | — | — | WO | claimed |