SCHEMBL728780

SCHEMBL728780

CC(CCCC(N)=O)C(=O)N1CCCCC1.NC(=O)CCCCC(N)=O

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 3/20 0.45
L3MBTL1 Q9Y468 3/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ATM Q13315 1/20 0.38
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.38
MMP8 P22894 1/20 0.38
EPHX2 P34913 2/20 0.37
DPP8 Q6V1X1 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HTT P42858 1/20 0.36
REN P00797 1/20 0.36
ACE P12821 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4639703 0.98 DPP7 (0.46) DPP7L3MBTL1MEN1KMT2ATDP1
SCHEMBL18395081 0.94 L3MBTL1 (0.54) DPP7L3MBTL1MEN1KMT2ATDP1
SCHEMBL727884 0.89 DPP7 (0.43) DPP7L3MBTL1MEN1KMT2ATDP1
SCHEMBL10710452 0.85 GAA (0.44) DPP7L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL13724662 0.84 HPGD (0.49) L3MBTL1MEN1KMT2AALDH1A1HTT
SCHEMBL15068892 0.84 HPGD (0.49) L3MBTL1MEN1KMT2AALDH1A1HTT
SCHEMBL16574601 0.80 DPP7 (0.45) DPP7L3MBTL1MMP1MMP2MMP8
SCHEMBL23241332 0.78 L3MBTL1 (0.44) DPP7L3MBTL1MEN1KMT2ATDP1
SCHEMBL8498746 0.78 L3MBTL1 (0.44) DPP7L3MBTL1MEN1KMT2ATDP1
SCHEMBL8489452 0.78 DPP7 (0.42) DPP7L3MBTL1MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2978810-B1 HEAT RESISTANT POLYAMIDE COMPOSITIONS DU PONT (US) 2021-02-24 EP claimed
EP-2307482-B1 LONG-TERM HEAT AGING RESISTANT POLYAMIDE COMPOSITIONS DU PONT (US) 2017-01-25 EP claimed
EP-2841504-B1 THERMOPLASTIC POLYAMIDE COMPOSITION DU PONT (US) 2016-11-30 EP claimed
EP-2307480-B1 HEAT RESISTANT THERMOPLASTIC ARTICLES INCLUDING CO-STABILIZERS DU PONT (US) 2016-08-17 EP claimed
EP-2978810-A1 HEAT RESISTANT POLYAMIDE COMPOSITIONS E. I. du Pont de Nemours and Company (US) 2016-02-03 EP claimed
EP-2307504-B1 THERMOPLASTIC ARTICLES INCLUDING POLYHYDROXY POLYMERS DU PONT (US) 2015-07-08 EP claimed
EP-2861667-A1 THERMOPLASTIC MELT-MIXED COMPOSITION WITH POLYETHEROL HEAT STABILIZER E.I. Du Pont De Nemours And Company (US) 2015-04-22 EP claimed
US-8952107-B2 Thermoplastic melt-mixed composition with polyetherol heat stabilizer E I DU PONT DE NEMOURS AND COMPANY (US) 2015-02-10 US claimed
WO-2014160564-A1 HEAT RESISTANT POLYAMIDE COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2014-10-02 WO claimed
US-20140288220-A1 HEAT RESISTANT POLYAMIDE COMPOSITIONS E I DU PONT DE NEMOURS AND COMPANY (US) 2014-09-25 US claimed
WO-2010014801-A1 HEAT RESISTANT MOLDED OR EXTRUDED THERMOPLASTIC ARTICLES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 WO claimed
WO-2010014810-A1 LONG-TERM HEAT AGING RESISTANT POLYAMIDE COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 WO claimed
WO-2010014785-A1 HEAT RESISTANT THERMOPLASTIC ARTICLES INCLUDING CO-STABILIZERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 WO claimed
WO-2010014795-A1 THERMOPLASTIC ARTICLES INCLUDING POLYHYDROXY POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 WO claimed
US-20100029815-A1 HEAT RESISTANT THERMOPLASTIC ARTICLES INCLUDING POLYHYDROXY POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 US claimed
US-20100028580-A1 HEAT RESISTANT THERMOPLASTIC ARTICLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 US claimed
US-20100029820-A1 LONG-TERM HEAT AGING RESISTANT POLYAMIDE COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 US claimed
US-20100029819-A1 HEAT RESISTANT MOLDED OR EXTRUDED THERMOPLASTIC ARTICLES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 US claimed
US-20100029821-A1 HEAT RESISTANT THERMOPLASTIC ARTICLES INCLUDING CO-STABILIZERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 US claimed
WO-2010014791-A1 HEAT RESISTANT THERMOPLASTIC ARTICLES INCLUDING POLYHYDROXY POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 WO claimed