Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 10/20 | 0.34 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740788 | 0.72 | POLB (0.34) | POLBEPHX2CTSKGCKCTSC | |
| SCHEMBL7269271 | 0.66 | POLB (0.39) | POLBEPHX2CTSKGCK | |
| SCHEMBL7299275 | 0.66 | POLB (0.39) | POLBEPHX2CTSKGCK | |
| SCHEMBL7269929 | 0.66 | POLB (0.39) | POLBEPHX2CTSKGCK | |
| SCHEMBL7269925 | 0.66 | POLB (0.39) | POLBEPHX2CTSKGCK | |
| SCHEMBL7269553 | 0.66 | POLB (0.39) | POLBEPHX2CTSKGCK | |
| SCHEMBL7269548 | 0.66 | POLB (0.39) | POLBEPHX2CTSKGCK | |
| SCHEMBL7269543 | 0.66 | POLB (0.39) | POLBEPHX2CTSKGCK | |
| SCHEMBL2041403 | 0.66 | MEN1 (0.46) | POLBEPHX2MEN1KMT2AALDH1A1 | |
| SCHEMBL2672708 | 0.65 | EPHX2 (0.60) | POLBEPHX2MEN1KMT2AGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |