Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | GCK | P35557 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7268413 | 0.84 | CTSK (0.38) | CTSK | |
| SCHEMBL9741080 | 0.82 | LNPEP (0.31) | — | |
| SCHEMBL7268400 | 0.79 | CTSK (0.34) | POLBCTSKCTSCGCK | |
| SCHEMBL7268382 | 0.78 | REN (0.46) | — | |
| SCHEMBL7268409 | 0.77 | POLB (0.30) | POLB | |
| SCHEMBL10714989 | 0.76 | LNPEP (0.32) | CTSKCTSC | |
| SCHEMBL10422486 | 0.74 | LNPEP (0.35) | — | |
| SCHEMBL7269773 | 0.73 | CTSC (0.38) | POLBCTSKEPHX2CTSCGCK | |
| SCHEMBL7269778 | 0.73 | CTSC (0.38) | POLBCTSKEPHX2CTSCGCK | |
| SCHEMBL7278883 | 0.72 | POLB (0.40) | POLBCTSKEPHX2CTSCGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104869-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1992-04-14 | — | — | US | disclosed |