Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | SERPINH1 | P50454 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2240208 | 0.78 | ALDH1A1 (0.43) | BRD4ALDH1A1KDM4ESMN1; SMN2PDK2 | |
| SCHEMBL12478771 | 0.77 | SERPINH1 (0.40) | BRD4SERPINH1ALDH1A1KDM4EABL1 | |
| SCHEMBL28041335 | 0.77 | SERPINH1 (0.43) | SERPINH1ALDH1A1KDM4ESMN1; SMN2ABL1 | |
| SCHEMBL7281163 | 0.76 | PDE3B (0.43) | SERPINH1ALDH1A1ABL1MEN1KMT2A | |
| SCHEMBL7288542 | 0.75 | SERPINH1 (0.41) | SERPINH1ALDH1A1ABL1PDK2MEN1 | |
| SCHEMBL17594685 | 0.74 | HTR6 (0.40) | BRD4ALDH1A1KDM4ESMN1; SMN2HTR6 | |
| SCHEMBL12362330 | 0.74 | BRD4 (0.42) | BRD4ALDH1A1KDM4ESMN1; SMN2POLB | |
| SCHEMBL2240754 | 0.71 | BRD4 (0.52) | BRD4ALDH1A1KDM4ESMN1; SMN2POLB | |
| SCHEMBL23412523 | 0.70 | BRD4 (0.39) | BRD4SERPINH1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL29706778 | 0.70 | BRD4 (0.51) | BRD4ALDH1A1KDM4ESMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313393-B1 | Benzoxazine compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4892872-A | ANTIEMETICS, ANTINAUSEA | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0313393-A2 | Benzoxazine compounds and pharmaceutical use thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-04-26 | — | — | EP | disclosed |