Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PRKDC | P78527 | 2/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 8/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.37 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1493885 | 0.79 | ALDH1A1 (0.61) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL2174504 | 0.77 | PRKDC (0.79) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL5698339 | 0.72 | ALDH1A1 (0.81) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL21577464 | 0.72 | ALDH1A1 (0.47) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL9860536 | 0.71 | SMN1; SMN2 (0.44) | ALDH1A1TSHRGAAERN1TLR2 | |
| SCHEMBL23202774 | 0.70 | GAA (0.64) | MGAMGAASIMGAM2CYP3A4 | |
| SCHEMBL30350284 | 0.70 | GAA (0.64) | MGAMGAASIMGAM2CYP3A4 | |
| SCHEMBL9860592 | 0.70 | PRKDC (0.49) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL7278938 | 0.70 | MGAM (0.53) | MGAMGAASIMGAM2MAPT | |
| 2-Methoxybenzaldehyde SCHEMBL5070004 | 0.69 | ALDH1A1 (0.54) | ALDH1A1KDM4ETDP1GAAERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557016-B1 | Naphthalene derivatives, processes for preparing the same, and synthetic intermediates therefor | TANABE SEIYAKU CO (JP) | 1996-06-19 | — | — | EP | disclosed |
| US-5342941-A | Bronchodilating agents | TANABE SEIYAKU CO., LTD. (JP) | 1994-08-30 | — | — | US | disclosed |
| EP-0557016-A1 | Naphthalene derivatives, processes for preparing the same, and synthetic intermediates therefor | TANABE SEIYAKU CO., LTD. (JP) | 1993-08-25 | — | — | EP | disclosed |