Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 2/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ERN1 | O75460 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515642 | 0.89 | PRKDC (1.00) | PRKDCALDH1A1MAPTLMNAHPGD | |
| SCHEMBL660822 | 0.85 | PRKDC (0.77) | PRKDCALDH1A1MAPTLMNAHPGD | |
| SCHEMBL28786078 | 0.85 | PRKDC (0.77) | PRKDCALDH1A1MAPTLMNAHPGD | |
| SCHEMBL1620606 | 0.81 | PRKDC (0.70) | PRKDCALDH1A1MAPTLMNAHPGD | |
| SCHEMBL30575778 | 0.81 | PRKDC (0.82) | PRKDCALDH1A1MAPTLMNAHPGD | |
| SCHEMBL30665931 | 0.80 | PRKDC (0.81) | PRKDCALDH1A1MAPTLMNAHPGD | |
| SCHEMBL18270047 | 0.80 | PRKDC (0.81) | PRKDCALDH1A1MAPTLMNAHPGD | |
| SCHEMBL698744 | 0.80 | PRKDC (0.81) | PRKDCALDH1A1MAPTLMNAHPGD | |
| SCHEMBL9860592 | 0.79 | PRKDC (0.49) | PRKDCALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL1620382 | 0.78 | LMNA (0.87) | PRKDCALDH1A1MAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1964925-B1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE 4-HYDROXY-1,2,3,4 -TETRAHYDROQUINOLINES | MITSUBISHI TANABE PHARMA CORP (JP) | 2016-03-30 | — | — | EP | disclosed |
| US-8754221-B2 | Optically active cyclic alcohol compound and method for preparing the same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2014-06-17 | — | — | US | disclosed |
| US-20130237708-A1 | Optically Active Cyclic Alcohol Compound And Method For Preparing The Same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-09-12 | — | — | US | disclosed |
| EP-2371820-B1 | Optically active cyclic alcohol compound and method for preparing the same | MITSUBISHI TANABE PHARMA CORP (JP) | 2013-08-28 | — | — | EP | disclosed |
| US-8471028-B2 | Optically active cyclic alcohol compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-06-25 | — | — | US | disclosed |
| EP-1944291-B1 | Optically active cyclic alcohol compound and method for producing same | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-06-13 | — | — | EP | disclosed |
| EP-2371820-A1 | Optically active cyclic alcohol compound and method for preparing the same | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-10-05 | — | — | EP | disclosed |
| US-20110196157-A1 | OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PREPARING THE SAME | MITSUBISHI TANABE PHARMA CORPORATION | 2011-08-11 | — | — | US | disclosed |
| US-7989627-B2 | Optically active cyclic alcohol compound and method for preparing the same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-08-02 | — | — | US | disclosed |
| US-7972836-B2 | Method of enzymatic optical resolution of racemic 4-hydroxy-1,2,3,4-tetrahydroquinoline | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-07-05 | — | — | US | disclosed |
| US-20090269821-A1 | Method for Preparing Optically Active 4-Hydroxy-1,2,3,4-Tetrahydroquinoline Compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-10-29 | — | — | US | disclosed |
| EP-1964925-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE 4-HYDROXY-1,2,3,4 -TETRAHYDROQUINOLINES | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-09-03 | — | — | EP | disclosed |
| EP-1944291-A1 | OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PRODUCING SAME | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-07-16 | — | — | EP | disclosed |
| EP-0557016-B1 | Naphthalene derivatives, processes for preparing the same, and synthetic intermediates therefor | TANABE SEIYAKU CO (JP) | 1996-06-19 | — | — | EP | disclosed |
| US-5342941-A | Bronchodilating agents | TANABE SEIYAKU CO., LTD. (JP) | 1994-08-30 | — | — | US | disclosed |
| EP-0401125-B1 | Biphenyl derivatives, process for preparing the same and intermediates therefor | TANABE SEIYAKU CO (JP) | 1994-08-24 | — | — | EP | disclosed |
| EP-0557016-A1 | Naphthalene derivatives, processes for preparing the same, and synthetic intermediates therefor | TANABE SEIYAKU CO., LTD. (JP) | 1993-08-25 | — | — | EP | disclosed |
| US-5233057-A | For treatment or prophylaxis of liver disorders | TANABE SEIYAKU CO., LTD. (JP) | 1993-08-03 | — | — | US | disclosed |
| US-5182404-A | Liver disorders | TANABE SEIYAKE CO., LTD. (JP) | 1993-01-26 | — | — | US | disclosed |
| US-5103023-A | Carboxy derivates with oxy subsitituents for treating liuer disorders | TANABE SEIYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110196157-A1 | OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PREPARING THE SAME | ADH1C, ADH1A, ADH5 | PRKDC 1741/4885ALDH1A1 25/4885MAPT 3358/4885 |
| US-20130237708-A1 | Optically Active Cyclic Alcohol Compound And Method For Preparing The Same | ADH1C, ADH1A, ADH5 | PRKDC 1741/4885ALDH1A1 25/4885MAPT 3358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.