Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7279235 | 0.86 | PRCP (0.44) | F2NPC1DPP4DPP8DPP9 | |
| SCHEMBL7284993 | 0.86 | NPC1 (0.47) | F2NPC1PREPDPP4 | |
| SCHEMBL10335959 | 0.84 | F2 (0.63) | F2HTR1AHTR7 | |
| SCHEMBL7267106 | 0.83 | TP53 (0.59) | F2DPP4DPP8DPP7TP53 | |
| SCHEMBL7279739 | 0.82 | UTS2R (0.43) | NAAA | |
| SCHEMBL7284906 | 0.79 | PRCP (0.44) | NPC1L3MBTL1DPP4DPP8DPP9 | |
| SCHEMBL7279154 | 0.79 | MEN1 (0.54) | NPC1PREPDPP4 | |
| SCHEMBL7284379 | 0.78 | MEN1 (0.50) | NPC1PREPDPP4 | |
| SCHEMBL10509497 | 0.78 | NPC1 (0.55) | F2NPC1NAAAPREPDPP4 | |
| SCHEMBL10509504 | 0.78 | NPC1 (0.55) | F2NPC1NAAAPREPDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277588-B1 | PROLINAL DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-03-24 | — | — | EP | claimed |
| EP-0277588-A1 | Prolinal derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-08-10 | — | — | EP | claimed |