Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10615160 | 0.92 | PRCP (0.49) | PRCPHRH3DPP4MEN1KMT2A | |
| SCHEMBL7279235 | 0.88 | PRCP (0.44) | PRCPHRH3DPP4MEN1KMT2A | |
| SCHEMBL7284993 | 0.88 | NPC1 (0.47) | TDP1DPP4MEN1KMT2AFAP | |
| SCHEMBL7278569 | 0.87 | KMT2A (0.49) | HRH3DPP4MEN1KMT2AFAP | |
| SCHEMBL7284635 | 0.85 | OPRD1 (0.44) | HRH3DPP4FAPDPP8DPP9 | |
| SCHEMBL10335879 | 0.83 | ACE (0.50) | PRCPDPP4CYP3A4CYP2C9PKM | |
| SCHEMBL7279739 | 0.81 | UTS2R (0.43) | HRH3 | |
| SCHEMBL7265568 | 0.81 | HPGD (0.52) | DPP4MEN1KMT2ADPP8DPP7 | |
| SCHEMBL7279154 | 0.81 | MEN1 (0.54) | DPP4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7275454 | 0.80 | CCR1 (0.45) | HRH3DPP4MEN1KMT2AFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277588-B1 | PROLINAL DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-03-24 | — | — | EP | claimed |
| EP-0277588-A1 | Prolinal derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-08-10 | — | — | EP | claimed |