Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7284993 | 0.86 | NPC1 (0.47) | POLB | |
| SCHEMBL7275293 | 0.83 | LMNA (0.45) | UTS2RCXCR4 | |
| SCHEMBL7278977 | 0.82 | F2 (0.53) | NAAA | |
| SCHEMBL7279235 | 0.81 | PRCP (0.44) | HRH3POLB | |
| SCHEMBL7284906 | 0.81 | PRCP (0.44) | HRH3 | |
| SCHEMBL7366315 | 0.81 | PDPK1 (0.40) | HRH3PDPK1NAAACYP1A2HCAR2 | |
| SCHEMBL7272889 | 0.81 | SIGMAR1 (0.43) | UTS2RCXCR4POLB | |
| SCHEMBL7278569 | 0.81 | KMT2A (0.49) | HRH3FKBP1ACYP1A2 | |
| SCHEMBL7284471 | 0.80 | DPP4 (0.47) | UTS2R | |
| SCHEMBL7279154 | 0.79 | MEN1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277588-B1 | PROLINAL DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-03-24 | — | — | EP | claimed |
| EP-0277588-A1 | Prolinal derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-08-10 | — | — | EP | claimed |
| US-5091406-A | Cognition activators | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-02-25 | — | — | US | disclosed |
| US-4977180-A | ANTIAMNESIA AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-12-11 | — | — | US | disclosed |