SCHEMBL7279648

CC(C)C[C@H](O)[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@@H](CC(=O)N(CC1CCCCC1)CC(C)(C)O)Cc1csc(N)n1

nearest known ligand 0.69

Predicted protein targets (top 2)

	gene	UniProt	supporting neighbours	confidence
▸	REN	P00797	20/20	0.69

▸	CTSD	P07339	1/20	0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7280725	1.00	REN (0.69)	RENCTSD
SCHEMBL7277617	1.00	REN (0.69)	RENCTSD
SCHEMBL7289751	0.92	REN (0.61)	RENCTSD
SCHEMBL7280171	0.91	REN (0.64)	RENCTSD
SCHEMBL7392928	0.89	REN (0.77)	RENCTSD
SCHEMBL7397145	0.89	REN (0.77)	RENCTSD
SCHEMBL7396287	0.89	REN (0.77)	RENCTSD
SCHEMBL7290842	0.89	REN (0.62)	RENCTSD
SCHEMBL7278110	0.88	REN (0.60)	RENCTSD
SCHEMBL7277111	0.87	REN (0.60)	RENCTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0589446-A1	N-(Hydroxyethyl)butanediamide derivatives as renin inhibitors	BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA)	1994-03-30	—	—	EP	claimed