Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290842 | 0.92 | REN (0.62) | RENCTSD | |
| SCHEMBL7277617 | 0.91 | REN (0.69) | RENCTSD | |
| SCHEMBL7280725 | 0.91 | REN (0.69) | RENCTSD | |
| SCHEMBL7279648 | 0.91 | REN (0.69) | RENCTSD | |
| SCHEMBL7394147 | 0.90 | REN (0.70) | RENCTSD | |
| SCHEMBL7278110 | 0.90 | REN (0.60) | RENCTSD | |
| SCHEMBL7289751 | 0.88 | REN (0.61) | RENCTSD | |
| SCHEMBL7287456 | 0.86 | REN (0.54) | REN | |
| SCHEMBL7389122 | 0.85 | REN (0.72) | RENCTSD | |
| SCHEMBL7392286 | 0.84 | REN (0.88) | RENCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589446-B1 | N-(Hydroxyethyl)butanediamide derivatives as renin inhibitors | BOEHRINGER INGELHEIM CA LTD (CA) | 1997-09-03 | — | — | EP | claimed |
| WO-1994007845-A1 | N-(HYDROXYETHYL)BUTANEDIAMIDE DERIVATIVES AS RENIN INHIBITORS | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1994-04-14 | — | — | WO | claimed |
| EP-0589446-A1 | N-(Hydroxyethyl)butanediamide derivatives as renin inhibitors | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1994-03-30 | — | — | EP | claimed |