Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | NPC1 | O15118 | 6/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | PKM | P14618 | 4/20 | 0.66 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.55 |
| ▸ | AURKA | O14965 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.52 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.52 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.52 |
| ▸ | RAF1 | P04049 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7272126 | 0.98 | ALDH1A1 (0.64) | ALDH1A1NPC1SMN1; SMN2KDM4ERAB9A | |
| Hydrochloric Acid SCHEMBL10846592 | 0.98 | ALDH1A1 (0.64) | ALDH1A1NPC1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL10960338 | 0.89 | ALDH1A1 (0.54) | ALDH1A1NPC1SMN1; SMN2KDM4ERAB9A | |
| Hydrochloric Acid SCHEMBL10961998 | 0.88 | ALDH1A1 (0.56) | ALDH1A1NPC1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL7272003 | 0.87 | ALDH1A1 (0.51) | ALDH1A1NPC1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL5591310 | 0.87 | ALDH1A1 (0.65) | ALDH1A1NPC1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL9636406 | 0.84 | ALDH1A1 (0.54) | ALDH1A1NPC1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL9635065 | 0.84 | HDAC3 (0.51) | ALDH1A1NPC1SMN1; SMN2KDM4ERAB9A | |
| Hydrochloric Acid SCHEMBL7271940 | 0.83 | ALDH1A1 (0.53) | ALDH1A1NPC1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL11228706 | 0.82 | ALDH1A1 (0.68) | ALDH1A1NPC1SMN1; SMN2KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904785-A | INOTROPIC AGENTS FOR CARDIOVASCULAR DISORDERS | ELI LILLY AND COMPANY (US) | 1990-02-27 | — | — | US | disclosed |
| US-4758574-A | 2-phenylimidazio (4,5-c) pyridines | ELI LILLY AND COMPANY (US) | 1988-07-19 | — | — | US | disclosed |
| US-4603139-A | 2-PHENYL-1H-IMIDAZOL(4,5-C)PYRIDINES, ANTICXOAGULANTS, CARDIOVASCULAR DISORDERS | BURROUGHS WELLCOME CO. | 1986-07-29 | — | — | US | disclosed |
| EP-0093593-A2 | Pyridine compounds | ELI LILLY AND COMPANY (US) | 1983-11-09 | — | — | EP | disclosed |
| EP-0079083-A1 | New imidazo[4,5-c]pyridine derivatives, processes for their preparation and pharmaceutical formulations containing such compounds | MERCK PATENT GmbH (DE) | 1983-05-18 | — | — | EP | disclosed |