Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.48 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9634597 | 0.87 | FGFR1 (0.42) | ALDH1A1KDM4EHPGDNPC1SMN1; SMN2 | |
| SCHEMBL7279680 | 0.87 | ALDH1A1 (0.66) | ALDH1A1KDM4EHPGDNPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7271945 | 0.86 | AURKA (0.57) | ALDH1A1KDM4EHPGDNPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10846592 | 0.85 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDNPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7272126 | 0.85 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDNPC1SMN1; SMN2 | |
| SCHEMBL10960338 | 0.85 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDNPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10961998 | 0.83 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDNPC1SMN1; SMN2 | |
| SCHEMBL30442918 | 0.83 | KDM4E (0.59) | ALDH1A1KDM4EHPGDSMN1; SMN2TP53 | |
| SCHEMBL7280891 | 0.83 | KDM4E (0.59) | ALDH1A1KDM4EHPGDSMN1; SMN2TP53 | |
| SCHEMBL7270830 | 0.83 | KDM4E (0.49) | ALDH1A1KDM4EHPGDNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904785-A | INOTROPIC AGENTS FOR CARDIOVASCULAR DISORDERS | ELI LILLY AND COMPANY (US) | 1990-02-27 | — | — | US | disclosed |
| US-4758574-A | 2-phenylimidazio (4,5-c) pyridines | ELI LILLY AND COMPANY (US) | 1988-07-19 | — | — | US | disclosed |
| EP-0093593-A2 | Pyridine compounds | ELI LILLY AND COMPANY (US) | 1983-11-09 | — | — | EP | disclosed |