Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.60 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.57 |
| ▸ | GBA1 | P04062 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29471350 | 1.00 | SPHK2 (0.60) | SPHK2SPHK1OPRD1GBA1 | |
| SCHEMBL27627908 | 0.95 | SPHK2 (0.66) | SPHK2SPHK1OPRD1GBA1 | |
| SCHEMBL25687586 | 0.91 | SPHK1 (0.62) | SPHK2SPHK1OPRD1 | |
| SCHEMBL27650694 | 0.88 | OPRD1 (0.55) | OPRD1 | |
| SCHEMBL25687560 | 0.88 | ALDH1A1 (0.56) | SPHK2SPHK1OPRD1 | |
| SCHEMBL18922677 | 0.86 | SPHK2 (0.63) | SPHK2SPHK1 | |
| SCHEMBL5888793 | 0.86 | OPRD1 (0.55) | OPRD1 | |
| SCHEMBL6797294 | 0.85 | SPHK2 (0.62) | SPHK2SPHK1 | |
| SCHEMBL25685938 | 0.85 | SPHK2 (0.61) | SPHK2SPHK1 | |
| SCHEMBL6797298 | 0.85 | SPHK2 (0.62) | SPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429984-B1 | Indole derivatives | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5124324-A | Psychological disorders, 5-hydroxy tryptamine antagonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0429984-A2 | Indole derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |