Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432717 | 0.85 | ALDH1A1 (0.38) | POLB | |
| SCHEMBL7289944 | 0.80 | KDM4E (0.38) | SMN1; SMN2POLB | |
| SCHEMBL1922886 | 0.72 | HSP90AA1 (0.37) | POLB | |
| SCHEMBL7948080 | 0.68 | KDM4E (0.38) | POLB | |
| SCHEMBL7948082 | 0.68 | KDM4E (0.38) | POLB | |
| SCHEMBL10608968 | 0.68 | CYP3A4 (0.32) | — | |
| SCHEMBL14335016 | 0.65 | POLB (0.37) | SMN1; SMN2POLB | |
| SCHEMBL28303367 | 0.65 | TPMT (0.38) | — | |
| SCHEMBL29580324 | 0.65 | CYP3A4 (0.38) | POLB | |
| Acetic Acid SCHEMBL7951725 | 0.65 | KDM4E (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567264-A | ADRENERGIC BLOCKING AGENTS | SYNTEX (U.S.A.) INC. (US) | 1986-01-28 | — | — | US | disclosed |
| US-4558129-A | Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade | SYNTEX (U.S.A.) INC. (US) | 1985-12-10 | — | — | US | disclosed |
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |
| EP-0126449-A1 | Cardioselective aryloxy- and arylthio-hydroxypropyl piperazinyl acetanilides wich affect calcium entry | SYNTEX (U.S.A.) INC. (US) | 1984-11-28 | — | — | EP | disclosed |