Sugi Predict

Sugi Predict / Compounds / SCHEMBL72800

SCHEMBL72800

SCHEMBL72800

CC(C)(C)OC(=O)N1C[C@H](O)[C@@H](O)C1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR1H2 P55055 1/20 0.56
▸ USP2 O75604 1/20 0.50
▸ SMN1; SMN2 Q16637 1/20 0.50
▸ CHRM2 P08172 1/20 0.47
▸ CHRM1 P11229 1/20 0.47
▸ CHRM3 P20309 1/20 0.47
▸ HPGD P15428 1/20 0.46
▸ RECQL P46063 1/20 0.44
▸ EPHX1 P07099 1/20 0.44
▸ DDB1 Q16531 1/20 0.42
▸ CRBN Q96SW2 1/20 0.42
▸ NAMPT P43490 1/20 0.42
▸ MEN1 O00255 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ MAPT P10636 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ EPHX2 P34913 1/20 0.41
▸ RORC P51449 1/20 0.41
▸ GPR119 Q8TDV5 1/20 0.41
▸ KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL917596 1.00 NR1H2 (0.56) NR1H2USP2SMN1; SMN2CHRM2CHRM1
SCHEMBL71583 1.00 NR1H2 (0.56) NR1H2USP2SMN1; SMN2CHRM2CHRM1
SCHEMBL666524 1.00 NR1H2 (0.56) NR1H2USP2SMN1; SMN2CHRM2CHRM1
SCHEMBL30287755 0.92 NR1H2 (0.53) NR1H2USP2SMN1; SMN2CHRM2CHRM1
SCHEMBL2441060 0.92 NR1H2 (0.53) NR1H2USP2SMN1; SMN2CHRM2CHRM1
SCHEMBL2441058 0.92 NR1H2 (0.53) NR1H2USP2SMN1; SMN2CHRM2CHRM1
SCHEMBL19420219 0.92 NR1H2 (0.53) NR1H2USP2SMN1; SMN2CHRM2CHRM1
SCHEMBL23288691 0.90 NR1H2 (0.51) NR1H2USP2SMN1; SMN2CHRM2CHRM1
SCHEMBL951953 0.90 NR1H2 (0.51) NR1H2USP2SMN1; SMN2CHRM2CHRM1
SCHEMBL951952 0.90 NR1H2 (0.51) NR1H2USP2SMN1; SMN2CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4719593-A1 ENANTIOSELECTIVE PREPARATION METHOD Immunahr AB (SE) 2026-04-08 — — EP disclosed
US-20260078093-A1 (4R)-3-(4-FLUORO-2-HYDROXYPHENYL)-4-METHYL-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOXIMIDAMIDE HYDROCHLORIDE AND DERMAL FORMULATIONS THEREOF IMMUNAHR AB (SE) 2026-03-19 — — US disclosed
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 — — US disclosed
WO-2025064683-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 — — WO disclosed
WO-2025064718-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 — — WO disclosed
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-20 — — US disclosed
WO-2024245895-A1 ENANTIOSELECTIVE PREPARATION METHOD ANAMAR AB (SE) 2024-12-05 — — WO disclosed
CN-117088777-A Method for preparing 2-nitrobiphenyl compound 南通泰禾化工股份有限公司 2023-11-21 — — CN disclosed
US-20230287021-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR STABILIZING TRANSTHYRETIN AND INHIBITING TRANSTHYRETIN MISFOLDING PROTEGO BIOPHARMA, INC. 2023-09-14 — — US disclosed
US-20230287021-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR STABILIZING TRANSTHYRETIN AND INHIBITING TRANSTHYRETIN MISFOLDING PROTEGO BIOPHARMA, INC. 2023-09-14 — — US disclosed
EP-1140924-A1 PIPERAZINE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-10-10 — — EP disclosed
WO-2000035915-A1 PIPERAZINE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-06-22 — — WO disclosed
US-6004956-A CHEMICAL INTERMEDIATES FOR BACTERICIDES BAYER AKTIENGESELLSCHAFT (DE) 1999-12-21 — — US disclosed
US-5532364-A FROM A DIHYDROPYRIDINE DERIVATIVE BAYER AKTIENGESELLSCHAFT (DE) 1996-07-02 — — US disclosed
US-5480879-A ANTIBACTERIAL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1996-01-02 — — US disclosed
US-5468742-A Antibacterial agents, feed additives BAYER AKTIENGESELLSCHAFT (DE) 1995-11-21 — — US disclosed
US-5436334-A Enantiomerically pure 2-oxa-5,8-diazabicyclo[4.3.0]nonanes and process for their preparation BAYER AKTIENGESELLSCHAFT (DE) 1995-07-25 — — US disclosed
EP-0151282-B1 OPTICALLY ACTIVE 3,4-BIS-(DIPHENYLPHOSPHINO)-PYRROLIDINE, RHODIUM COMPLEXES CONTAINING THEM AS CHIRAL LIGANDS, AND THEIR USE Degussa Aktiengesellschaft (DE) 1988-09-07 — — EP disclosed
US-4634775-A HYDROGENATION CATALYSTS FOR ACYLAMINO-ACRYLIC ACIDS DEGUSSA AKTIENGESELLSCHAFT (DE) 1987-01-06 — — US disclosed
EP-0151282-A1 Optically active 3,4-bis-(diphenylphosphino)-pyrrolidine, rhodium complexes containing them as chiral ligands, and their use Degussa Aktiengesellschaft (DE) 1985-08-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230287021-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR STABILIZING TRANSTHYRETIN AND INHIBITING TRANSTHYRETIN MISFOLDING TTR, TTPA, TNNC1 NR1H2 3316/4885USP2 2418/4885SMN1; SMN2 68/4885
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS NR1H2 3045/4885USP2 1614/4885SMN1; SMN2 1694/4885
US-20260078093-A1 (4R)-3-(4-FLUORO-2-HYDROXYPHENYL)-4-METHYL-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOXIMIDAMIDE HYDROCHLORIDE AND DERMAL FORMULATIONS THEREOF HTR2B, HRH4, HTR3B NR1H2 741/4885USP2 4562/4885SMN1; SMN2 3567/4885
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS NR1H2 2741/4885USP2 1781/4885SMN1; SMN2 1576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.