Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.55 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3264030 | 0.89 | NR4A2 (0.61) | NR4A2CREBBPLMNAALDH1A1RAB9A | |
| SCHEMBL7280152 | 0.86 | NR4A2 (0.51) | NR4A2CREBBPLMNAALDH1A1RAB9A | |
| SCHEMBL7280001 | 0.80 | HTR2C (0.58) | NR4A2CREBBPLMNAALDH1A1RAB9A | |
| SCHEMBL730525 | 0.77 | NR4A2 (0.69) | NR4A2CREBBPLMNAALDH1A1RAB9A | |
| SCHEMBL14793753 | 0.76 | TDP1 (0.52) | NR4A2LMNAALDH1A1RAB9AKMT2A | |
| SCHEMBL7835246 | 0.76 | TDP1 (0.52) | NR4A2LMNAALDH1A1CYP2C9TSHR | |
| Hydrochloric Acid SCHEMBL30718988 | 0.76 | NR4A2 (0.67) | NR4A2CREBBPLMNAALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL28308377 | 0.76 | NR4A2 (0.67) | NR4A2CREBBPLMNAALDH1A1RAB9A | |
| SCHEMBL7636009 | 0.75 | GABRA1 (0.60) | NR4A2CREBBPLMNARAB9AGPR84 | |
| SCHEMBL5805847 | 0.74 | NR4A2 (0.65) | NR4A2CREBBPLMNAALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429984-B1 | Indole derivatives | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5124324-A | Psychological disorders, 5-hydroxy tryptamine antagonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0429984-A2 | Indole derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |