Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.51 |
| ▸ | PRCP | P42785 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7292650 | 0.81 | ALDH1A1 (0.47) | SLC18A3ALDH1A1 | |
| SCHEMBL7281890 | 0.81 | SLC18A3 (0.76) | SLC18A3PRCPCARM1PRMT6 | |
| SCHEMBL12123733 | 0.81 | PRCP (0.55) | PRCPCARM1PRMT6BACE1CYP1A2 | |
| SCHEMBL7289453 | 0.81 | TDP1 (0.64) | ALDH1A1CYP2D6MEN1KMT2ALMNA | |
| SCHEMBL4253158 | 0.80 | PRCP (0.55) | PRCPCARM1PRMT6NPY2RBACE1 | |
| SCHEMBL14282940 | 0.79 | ALDH1A1 (0.52) | PRCPNPY2RALDH1A1KMT2ALMNA | |
| SCHEMBL4695183 | 0.78 | PRCP (0.52) | PRCPCARM1PRMT6BACE1TP53 | |
| SCHEMBL4072745 | 0.77 | PRCP (0.49) | PRCPCARM1PRMT6NPY2RBACE1 | |
| SCHEMBL10364801 | 0.77 | TDP1 (0.59) | ALDH1A1CYP2D6MEN1KMT2ALMNA | |
| SCHEMBL10560753 | 0.77 | TMEM97 (0.59) | BACE1ALDH1A1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4603135-A | HYPOTENSIVE AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-07-29 | — | — | US | disclosed |
| EP-0138505-A2 | Dihydropyridine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-04-24 | — | — | EP | disclosed |