Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280252 | 1.00 | CTNNB1 (0.52) | CTNNB1FOLH1TDP1HRH4SLC1A3 | |
| SCHEMBL5953914 | 0.87 | FOLH1 (0.66) | CTNNB1FOLH1TDP1HRH4MME | |
| SCHEMBL6677809 | 0.86 | CTNNB1 (0.63) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL10521941 | 0.86 | SIGMAR1 (0.53) | CTNNB1FOLH1TDP1HRH4KMT2A | |
| SCHEMBL10521472 | 0.85 | SIGMAR1 (0.52) | CTNNB1FOLH1TDP1HRH4KMT2A | |
| SCHEMBL7268294 | 0.84 | CTNNB1 (0.58) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL7287691 | 0.84 | CTNNB1 (0.58) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL7267021 | 0.84 | CTNNB1 (0.58) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL10521224 | 0.83 | CTNNB1 (0.55) | CTNNB1FOLH1TDP1HRH4SLC1A3 | |
| SCHEMBL9556717 | 0.83 | CTNNB1 (0.48) | CTNNB1FOLH1TDP1HRH4SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506356-A | RENIN INHIBITORS; HYPOTENSIVE AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| US-5481036-A | RENIN INHIBITORS, HYPOTENSIVE AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| US-5319082-A | N-acylamino acid derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-06-07 | — | — | US | disclosed |
| US-5240924-A | Dipeptide hypotensives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-31 | — | — | US | disclosed |
| US-5122523-A | Hypotensive agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1992-06-16 | — | — | US | disclosed |
| EP-0309766-A2 | N-acylamino acid derivatives and their use | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-04-05 | — | — | EP | disclosed |