Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.41 |
| ▸ | PTGIR | P43119 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | HPN | P05981 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7275902 | 0.93 | POLB (0.42) | POLBTDP1TMPRSS6PTGIRAR | |
| SCHEMBL7276310 | 0.88 | ITGB3 (0.48) | ITGB3ITGA2BALDH1A1SMN1; SMN2ITGAV | |
| SCHEMBL7275113 | 0.88 | ITGB3 (0.48) | ITGB3ITGA2BALDH1A1SMN1; SMN2ITGAV | |
| SCHEMBL7273468 | 0.87 | ITGB3 (0.54) | ITGB3ITGA2BALDH1A1SMN1; SMN2ITGAV | |
| SCHEMBL7276387 | 0.87 | ITGB3 (0.54) | ITGB3ITGA2BALDH1A1SMN1; SMN2ITGAV | |
| SCHEMBL7281368 | 0.84 | ITGB3 (0.38) | ITGB3ITGA2BITGAV | |
| SCHEMBL7283779 | 0.84 | ITGB3 (0.49) | ITGB3ITGA2B | |
| SCHEMBL7275315 | 0.83 | ITGB3 (0.43) | ITGB3ITGA2BALDH1A1ITGAVLMNA | |
| SCHEMBL7272558 | 0.83 | ITGB3 (0.42) | ITGB3ITGA2BALDH1A1SMN1; SMN2PLAU | |
| SCHEMBL7271733 | 0.82 | AR (0.49) | POLBTDP1PTGIRARALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |