Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.48 |
| ▸ | ITGAV | P06756 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275113 | 1.00 | ITGB3 (0.48) | ITGB3ITGA2BITGAVALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7272660 | 0.92 | ITGB3 (0.43) | ITGB3ITGA2BITGAVALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7273834 | 0.92 | ITGB3 (0.43) | ITGB3ITGA2BITGAVALDH1A1LMNA | |
| SCHEMBL7276387 | 0.90 | ITGB3 (0.54) | ITGB3ITGA2BITGAVALDH1A1LMNA | |
| SCHEMBL7273468 | 0.90 | ITGB3 (0.54) | ITGB3ITGA2BITGAVALDH1A1LMNA | |
| SCHEMBL7284072 | 0.90 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTNR1H4NPC1 | |
| SCHEMBL7280312 | 0.88 | POLB (0.43) | ITGB3ITGA2BITGAVALDH1A1LMNA | |
| SCHEMBL7275315 | 0.85 | ITGB3 (0.43) | ITGB3ITGA2BITGAVALDH1A1LMNA | |
| SCHEMBL7272558 | 0.85 | ITGB3 (0.42) | ITGB3ITGA2BITGAVALDH1A1F2 | |
| Water SCHEMBL8881986 | 0.84 | ITGB3 (0.55) | ITGB3ITGA2BITGAVF2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |