Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.68 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | CTSK | P43235 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 2/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | REN | P00797 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28184491 | 1.00 | CTRB1 (0.68) | CTRB1TRPM8ALDH1A1ALOX15ABCB1 | |
| SCHEMBL10966776 | 0.93 | CTRB1 (0.61) | CTRB1TRPM8ALDH1A1ALOX15ABCB1 | |
| SCHEMBL7682035 | 0.92 | CTRB1 (0.72) | CTRB1TRPM8ALDH1A1ALOX15CTSL | |
| SCHEMBL7682037 | 0.92 | CTRB1 (0.72) | CTRB1TRPM8ALDH1A1ALOX15CTSL | |
| SCHEMBL10964829 | 0.89 | CTRB1 (0.57) | CTRB1TRPM8ALDH1A1ALOX15SYK | |
| SCHEMBL14531561 | 0.89 | SYK (0.60) | CTRB1TRPM8ALDH1A1ALOX15ABCB1 | |
| SCHEMBL555191 | 0.89 | CTRB1 (0.57) | CTRB1TRPM8ALDH1A1ALOX15ABCB1 | |
| SCHEMBL79250 | 0.89 | CTRB1 (0.57) | CTRB1TRPM8ALDH1A1ALOX15ABCB1 | |
| SCHEMBL14530318 | 0.89 | SYK (0.60) | CTRB1TRPM8ALDH1A1ALOX15ABCB1 | |
| SCHEMBL10964840 | 0.89 | CTRB1 (0.57) | CTRB1TRPM8ALDH1A1ALOX15SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0136883-A2 | Enkephalinase inhibitors | E.R. Squibb & Sons, Inc. (US) | 1985-04-10 | — | — | EP | disclosed |