Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.72 |
| ▸ | TACR1 | P25103 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 3/20 | 0.52 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682037 | 1.00 | CTRB1 (0.72) | CTRB1TACR1CTSLCTSKCTSB | |
| SCHEMBL7280375 | 0.92 | CTRB1 (0.68) | CTRB1TACR1CTSLCTSKCTSB | |
| SCHEMBL28184491 | 0.92 | CTRB1 (0.68) | CTRB1TACR1CTSLCTSKCTSB | |
| SCHEMBL6157326 | 0.90 | CTRB1 (0.74) | CTRB1TACR1CTSLCTSKCTSB | |
| SCHEMBL6157333 | 0.90 | CTRB1 (0.74) | CTRB1TACR1CTSLCTSKCTSB | |
| SCHEMBL7360205 | 0.87 | CTRB1 (0.62) | CTRB1TACR1CTSLCTSKCTSB | |
| SCHEMBL7360200 | 0.87 | CTRB1 (0.62) | CTRB1TACR1CTSLCTSKCTSB | |
| SCHEMBL14119009 | 0.87 | ATM (0.62) | CTRB1CTSLCTSKCTSBCTSS | |
| SCHEMBL15928906 | 0.87 | ATM (0.62) | CTRB1CTSLCTSKCTSBCTSS | |
| SCHEMBL1823130 | 0.86 | CTRB1 (0.55) | CTRB1CTSLCTSKCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021405-B1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF HCMV INFECTIONS | BOEHRINGER INGELHEIM CA LTD (CA) | 2002-09-25 | — | — | EP | disclosed |
| US-6242439-B1 | Azetidinone derivatives for the treatment of HCMV infections | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2001-06-05 | — | — | US | disclosed |