Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 13/20 | 0.50 |
| ▸ | OXTR | P30559 | 2/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2307 | 0.86 | LTB4R2 (0.54) | LTB4R2OXTRAVPR1AAGTR1ACHE | |
| SCHEMBL2306 | 0.86 | LTB4R2 (0.54) | LTB4R2OXTRAVPR1AAGTR1ACHE | |
| SCHEMBL7270253 | 0.85 | LTB4R2 (0.54) | LTB4R2OXTRAVPR1AAGTR1FFAR1 | |
| SCHEMBL7272113 | 0.85 | LTB4R2 (0.54) | LTB4R2OXTRAVPR1AAGTR1ACHE | |
| SCHEMBL7271019 | 0.82 | LTB4R2 (0.47) | LTB4R2AGTR1 | |
| SCHEMBL7278162 | 0.81 | OXTR (0.40) | OXTRAVPR1AFFAR1AKR1B1NR1H4 | |
| SCHEMBL2100 | 0.79 | LTB4R2 (0.55) | LTB4R2OXTRAVPR1AAGTR1FFAR1 | |
| SCHEMBL2099 | 0.79 | LTB4R2 (0.55) | LTB4R2OXTRAVPR1AAGTR1FFAR1 | |
| SCHEMBL2776 | 0.79 | LTB4R2 (0.55) | LTB4R2OXTRAVPR1AAGTR1ACHE | |
| SCHEMBL2445 | 0.74 | LTB4R2 (0.53) | LTB4R2OXTRAVPR1AAGTR1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443983-B1 | Acyl compounds | CIBA GEIGY AG (CH) | 1996-02-28 | — | — | EP | disclosed |