Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 10/20 | 0.55 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2099 | 1.00 | LTB4R2 (0.55) | LTB4R2OXTRAVPR1AAGTR1GPR119 | |
| SCHEMBL2776 | 0.91 | LTB4R2 (0.55) | LTB4R2OXTRAVPR1AAGTR1FFAR1 | |
| SCHEMBL7270253 | 0.89 | LTB4R2 (0.54) | LTB4R2OXTRAVPR1AAGTR1GPR119 | |
| SCHEMBL2307 | 0.86 | LTB4R2 (0.54) | LTB4R2OXTRAVPR1AAGTR1FFAR1 | |
| SCHEMBL2306 | 0.86 | LTB4R2 (0.54) | LTB4R2OXTRAVPR1AAGTR1FFAR1 | |
| SCHEMBL7272113 | 0.83 | LTB4R2 (0.54) | LTB4R2OXTRAVPR1AAGTR1FFAR1 | |
| SCHEMBL7280389 | 0.79 | LTB4R2 (0.50) | LTB4R2OXTRAVPR1AAGTR1FFAR1 | |
| SCHEMBL2934 | 0.79 | GPR119 (0.43) | OXTRAVPR1AGPR119 | |
| SCHEMBL3537 | 0.78 | MEN1 (0.44) | OXTRAVPR1AFFAR1AKR1B1OPRM1 | |
| SCHEMBL3536 | 0.78 | MEN1 (0.44) | OXTRAVPR1AFFAR1AKR1B1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965592-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| US-5399578-A | Hypotensive; valsartan; high blood pressure and cardiac insufficiency | CIBA-GEIGY CORP (US) | 1995-03-21 | — | — | US | disclosed |