Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278452 | 0.89 | REN (1.00) | REN | |
| SCHEMBL7280457 | 0.89 | REN (1.00) | REN | |
| SCHEMBL9014810 | 0.88 | REN (0.81) | REN | |
| SCHEMBL7278484 | 0.84 | REN (0.81) | REN | |
| SCHEMBL9014804 | 0.80 | REN (1.00) | REN | |
| SCHEMBL7281276 | 0.80 | REN (1.00) | REN | |
| SCHEMBL7281059 | 0.79 | REN (0.66) | REN | |
| SCHEMBL7427995 | 0.78 | REN (0.51) | REN | |
| SCHEMBL9632647 | 0.77 | REN (0.53) | REN | |
| SCHEMBL9632624 | 0.76 | REN (0.64) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545838-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1996-08-13 | — | — | US | disclosed |
| US-5098924-A | Hypotensive agents and angiotensin II inhibitors | E. R. SQUIBB & SONS, INC. (US) | 1992-03-24 | — | — | US | disclosed |
| EP-0452587-A1 | Dihydroxy sulfonamide and sulfinamide renin inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1991-10-23 | — | — | EP | disclosed |