Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281720 | 0.94 | KCNH2 (0.62) | KMT2AKCNH2CACNA1GKDM4ERECQL | |
| SCHEMBL7288432 | 0.92 | MEN1 (0.69) | L3MBTL1KMT2AMEN1HTTKDM4E | |
| SCHEMBL7288616 | 0.89 | CYP2D6 (0.65) | L3MBTL1KMT2AMEN1HTTKDM4E | |
| SCHEMBL10837247 | 0.89 | KMT2A (0.58) | L3MBTL1KMT2AMEN1CACNA1GHTT | |
| SCHEMBL10835709 | 0.88 | CYP2D6 (0.66) | L3MBTL1KMT2AMEN1KDM4ECYP2D6 | |
| SCHEMBL7289205 | 0.86 | CYP2D6 (0.54) | KMT2AMEN1KCNH2HTTKDM4E | |
| SCHEMBL7288741 | 0.85 | USP2 (0.65) | L3MBTL1KMT2AMEN1HTTCYP2D6 | |
| SCHEMBL7288797 | 0.85 | CYP2D6 (0.65) | L3MBTL1KMT2AMEN1KDM4ECYP2D6 | |
| SCHEMBL7288820 | 0.83 | CYP2D6 (0.64) | L3MBTL1KMT2AMEN1KDM4ECYP2D6 | |
| SCHEMBL7282602 | 0.82 | MEN1 (0.56) | L3MBTL1KMT2AMEN1HTTCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567264-A | ADRENERGIC BLOCKING AGENTS | SYNTEX (U.S.A.) INC. (US) | 1986-01-28 | — | — | US | disclosed |
| EP-0126449-A1 | Cardioselective aryloxy- and arylthio-hydroxypropyl piperazinyl acetanilides wich affect calcium entry | SYNTEX (U.S.A.) INC. (US) | 1984-11-28 | — | — | EP | disclosed |