Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 13/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10835709 | 0.97 | CYP2D6 (0.66) | CYP2D6L3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL7288820 | 0.94 | CYP2D6 (0.64) | CYP2D6L3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL7288432 | 0.92 | MEN1 (0.69) | CYP2D6L3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL7288741 | 0.91 | USP2 (0.65) | CYP2D6L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL7282202 | 0.89 | CYP2D6 (0.59) | CYP2D6L3MBTL1MAPK1LMNANPSR1 | |
| SCHEMBL7282602 | 0.89 | MEN1 (0.56) | CYP2D6L3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL7291652 | 0.88 | KMT2A (0.59) | CYP2D6L3MBTL1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL7300682 | 0.87 | LMNA (0.58) | CYP2D6MEN1KMT2ALMNANPSR1 | |
| SCHEMBL7288616 | 0.87 | CYP2D6 (0.65) | CYP2D6L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL7281734 | 0.85 | CYP2D6 (0.58) | CYP2D6L3MBTL1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567264-A | ADRENERGIC BLOCKING AGENTS | SYNTEX (U.S.A.) INC. (US) | 1986-01-28 | — | — | US | disclosed |
| EP-0126449-A1 | Cardioselective aryloxy- and arylthio-hydroxypropyl piperazinyl acetanilides wich affect calcium entry | SYNTEX (U.S.A.) INC. (US) | 1984-11-28 | — | — | EP | disclosed |