Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288432 | 0.89 | MEN1 (0.69) | MEN1KMT2ALMNANPSR1L3MBTL1 | |
| SCHEMBL7288797 | 0.89 | CYP2D6 (0.65) | MEN1KMT2ALMNANPSR1L3MBTL1 | |
| SCHEMBL7288741 | 0.89 | USP2 (0.65) | MEN1KMT2ALMNANPSR1L3MBTL1 | |
| SCHEMBL7279366 | 0.87 | CYP2D6 (0.49) | MEN1KMT2AL3MBTL1CYP2D6MAPT | |
| SCHEMBL7280914 | 0.86 | CYP2D6 (0.52) | MEN1KMT2ALMNANPSR1HTT | |
| SCHEMBL7291959 | 0.86 | KMT2A (0.51) | MEN1KMT2ALMNANPSR1CYP2D6 | |
| SCHEMBL10835709 | 0.85 | CYP2D6 (0.66) | MEN1KMT2AL3MBTL1CYP2D6POLB | |
| SCHEMBL7278589 | 0.84 | KMT2A (0.60) | MEN1KMT2ALMNANPSR1L3MBTL1 | |
| SCHEMBL7288616 | 0.84 | CYP2D6 (0.65) | MEN1KMT2ALMNANPSR1L3MBTL1 | |
| SCHEMBL7288820 | 0.83 | CYP2D6 (0.64) | MEN1KMT2AL3MBTL1CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567264-A | ADRENERGIC BLOCKING AGENTS | SYNTEX (U.S.A.) INC. (US) | 1986-01-28 | — | — | US | disclosed |
| EP-0126449-A1 | Cardioselective aryloxy- and arylthio-hydroxypropyl piperazinyl acetanilides wich affect calcium entry | SYNTEX (U.S.A.) INC. (US) | 1984-11-28 | — | — | EP | disclosed |