SCHEMBL728056

SCHEMBL728056

CCOC(=O)C(CC(=O)O)N(CC)[Si](OC)(OC)OC

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
CYP2D6 P10635 1/20 0.32
HTT P42858 2/20 0.31
LMNA P02545 1/20 0.31
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP1A2 P05177 1/20 0.31
CDC7 O00311 1/20 0.30
DBF4 Q9UBU7 1/20 0.30
CTSK P43235 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL730180 0.92
SCHEMBL728025 0.88 LMNA (0.30) HTTLMNA
SCHEMBL730378 0.87 ALDH1A1 (0.32) ALDH1A1CYP2D6HTTLMNAMEN1
SCHEMBL728095 0.81
SCHEMBL728055 0.75 ZDHHC7 (0.31) LMNA
SCHEMBL730337 0.75 LMNA (0.30) HTTLMNA
SCHEMBL730206 0.75 ALDH1A1 (0.37) ALDH1A1CYP2D6HTTLMNAMEN1
SCHEMBL27450027 0.71 ALDH1A1 (0.35) ALDH1A1CYP2D6HTTLMNAMEN1
SCHEMBL730207 0.71 MAPT (0.32)
SCHEMBL28427263 0.71 MEN1 (0.31) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP claimed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP disclosed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US disclosed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US disclosed