Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 8/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27196374 | 1.00 | CTSL (0.46) | CTSLCTSBCTSKTRPM8TSHR | |
| SCHEMBL15642921 | 0.90 | CTSL (0.48) | CTSLCTSBCTSKTRPM8TSHR | |
| Hydrochloric Acid SCHEMBL15258725 | 0.89 | CTSL (0.47) | CTSLCTSBCTSKTRPM8TSHR | |
| SCHEMBL5006990 | 0.85 | TSHR (0.50) | CTSLCTSBCTSKTSHRTAAR1 | |
| SCHEMBL5006985 | 0.85 | TSHR (0.50) | CTSLCTSBCTSKTSHRTAAR1 | |
| SCHEMBL28923696 | 0.85 | TSHR (0.50) | CTSLCTSBCTSKTSHRTAAR1 | |
| SCHEMBL6649338 | 0.85 | TSHR (0.54) | CTSLCTSBCTSKTSHRTAAR1 | |
| SCHEMBL4677170 | 0.81 | TSHR (0.54) | CTSLCTSBCTSKTSHRTAAR1 | |
| SCHEMBL7279522 | 0.81 | CTSL (0.46) | CTSLCTSBCTSKTSHRNAAA | |
| SCHEMBL23744979 | 0.80 | CTSL (0.50) | CTSLCTSBCTSKTSHRTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780632-A | Imide derivatives and their production and use | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |
| EP-0464846-B1 | Imide derivatives, and their production and use | SUMITOMO PHARMA (JP) | 1998-04-22 | — | — | EP | disclosed |
| US-5532372-A | Imide derivatives, and their production and use | SUMITOMO PHARMACEUTICALS COMPANY, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0464846-A1 | Imide derivatives, and their production and use | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-01-08 | — | — | EP | disclosed |