Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | EBP | Q15125 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL72806 | 1.00 | CCR3 (0.46) | CCR3HTR1DHTR1BMCHR1CCR2 | |
| SCHEMBL74318 | 0.91 | CCR3 (0.44) | CCR3HTR1DHTR1BMCHR1CCR2 | |
| SCHEMBL74317 | 0.91 | CCR3 (0.44) | CCR3HTR1DHTR1BMCHR1CCR2 | |
| SCHEMBL74047 | 0.90 | CCR3 (0.48) | CCR3HTR1DHTR1BMCHR1CCR2 | |
| SCHEMBL74046 | 0.90 | CCR3 (0.48) | CCR3HTR1DHTR1BMCHR1CCR2 | |
| SCHEMBL74545 | 0.83 | CCR3 (0.43) | CCR3MCHR1CCR2KMT2APLA2G1B | |
| SCHEMBL74546 | 0.83 | CCR3 (0.43) | CCR3MCHR1CCR2KMT2APLA2G1B | |
| SCHEMBL15545163 | 0.80 | MCHR1 (0.41) | CCR3HTR1DHTR1BMCHR1CCR2 | |
| SCHEMBL17022769 | 0.80 | MCHR1 (0.41) | CCR3HTR1DHTR1BMCHR1CCR2 | |
| SCHEMBL20448230 | 0.80 | SRPK1 (0.44) | CCR3HTR1DHTR1BMCHR1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045422-B2 | Piperidine derivatives with pesticidal properties | SYNGENTA PARTICIPATIONS AG (CH) | 2015-06-02 | — | — | US | disclosed |
| US-20130310399-A1 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-11-21 | — | — | US | disclosed |
| US-8546569-B2 | Chemical compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| EP-1763302-B1 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-03-06 | — | — | EP | disclosed |
| US-20120270885-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-10-25 | — | — | US | disclosed |
| US-8129534-B2 | Chemical compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20090042938-A1 | Chemical Compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270885-A1 | CHEMICAL COMPOUNDS | H1-0, CHRM1, MRM1 | CCR3 690/4885HTR1D 1979/4885HTR1B 3034/4885 |
| US-20090042938-A1 | Chemical Compounds | CHRM1, MRM1, H1-0 | CCR3 808/4885HTR1D 1916/4885HTR1B 2836/4885 |
| US-20130310399-A1 | CHEMICAL COMPOUNDS | ACHE, CHRM1, CHRM2 | CCR3 1630/4885HTR1D 1933/4885HTR1B 3520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.