SCHEMBL728090

SCHEMBL728090

COC(CCCCN)(OC)O[SiH3]

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 1/20 0.33
DNM1 Q05193 5/20 0.32
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA3 P07451 2/20 0.32
CA4 P22748 2/20 0.32
CA6 P23280 2/20 0.32
CA5A P35218 2/20 0.32
CA7 P43166 2/20 0.32
CA9 Q16790 2/20 0.32
CA14 Q9ULX7 2/20 0.32
CA5B Q9Y2D0 2/20 0.32
TSHR P16473 2/20 0.32
LMNA P02545 1/20 0.32
BLM P54132 1/20 0.32
FDPS P14324 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18037050 0.98 DNM1 (0.36) NFKB1DNM1CA12CA1CA2
SCHEMBL23579739 0.81 CA12 (0.41) CA12CA1CA2CA3CA4
SCHEMBL17530083 0.79 KIF11 (0.34) NFKB1DNM1CA12CA1CA2
SCHEMBL25278222 0.76 TSHR (0.38) TSHRLMNAFDPSMEN1KMT2A
SCHEMBL730419 0.76
SCHEMBL728407 0.76
SCHEMBL25274570 0.76 TSHR (0.38) TSHRLMNAFDPSMEN1KMT2A
SCHEMBL25275021 0.76 TSHR (0.38) TSHRLMNAFDPSMEN1KMT2A
SCHEMBL25277174 0.76 TSHR (0.38) TSHRLMNAFDPSMEN1KMT2A
SCHEMBL25272519 0.76 TSHR (0.38) TSHRLMNAFDPSMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP claimed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
EP-2852650-A1 CMP COMPOSITION CONTAINING ZIRCONIA PARTICLES AND METHOD OF USE Cabot Microelectronics Corporation (US) 2015-04-01 EP disclosed
WO-2013177110-A1 CMP COMPOSITION CONTAINING ZIRCONIA PARTICLES AND METHOD OF USE CABOT MICROELECTRONICS CORPORATION (US) 2013-11-28 WO disclosed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP disclosed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US disclosed
EP-2393861-A1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY Momentive Performance Materials Inc. (US) 2011-12-14 EP disclosed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US disclosed
WO-2010091338-A1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-08-12 WO disclosed
US-4496363-A Antimicrobial fabrics UOP INC. (US) 1985-01-29 US disclosed