Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.55 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.55 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | FPR2 | P25090 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278749 | 0.90 | CYP3A4 (0.61) | POLBMAPTITGB1ITGA4ITGB7 | |
| SCHEMBL6803415 | 0.87 | BLM (0.56) | POLBMAPTITGB1ITGA4ITGB7 | |
| SCHEMBL27230807 | 0.86 | POLB (0.74) | POLBITGB1ITGA4ITGB7KMT2A | |
| SCHEMBL7266885 | 0.86 | POLB (0.74) | POLBITGB1ITGA4ITGB7KMT2A | |
| SCHEMBL7295919 | 0.83 | KMT2A (0.57) | POLBITGB1ITGA4KMT2AFPR2 | |
| SCHEMBL9556460 | 0.81 | ADORA2A (0.58) | ITGB1ITGA4ITGB7KMT2AFPR2 | |
| SCHEMBL4361126 | 0.77 | ITGB3 (0.64) | KMT2AFPR2CA2ITGB3ITGA2B | |
| SCHEMBL8765951 | 0.77 | LDHA (0.63) | ITGA4ITGB7KMT2AFPR2CA2 | |
| SCHEMBL10663117 | 0.77 | LDHA (0.63) | ITGA4ITGB7KMT2AFPR2CA2 | |
| SCHEMBL6438360 | 0.77 | ITGB3 (0.64) | KMT2AFPR2CA2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989010751-A1 | FUNCTIONALIZED PEPTIDYL AMINODIOLS AND -TRIOLS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |
| EP-0341602-A2 | Renin-inhibiting functionalized peptidyl aminodiols and - triols | ABBOTT LABORATORIES (US) | 1989-11-15 | — | — | EP | disclosed |
| EP-0307837-A2 | Renin-inhibiting peptidyl heterocycles | ABBOTT LABORATORIES (US) | 1989-03-22 | — | — | EP | disclosed |