Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28358210 | 0.84 | KDM4E (0.40) | KDM4EALDH1A1TSHR | |
| SCHEMBL16287666 | 0.84 | KDM4E (0.40) | KDM4EALDH1A1TSHR | |
| SCHEMBL7444200 | 0.75 | USP30 (0.37) | ALOX5 | |
| SCHEMBL9297595 | 0.75 | USP30 (0.37) | ALOX5 | |
| SCHEMBL28517018 | 0.74 | KDM4E (0.39) | KDM4EALDH1A1TSHR | |
| SCHEMBL3161028 | 0.72 | KDM4E (0.41) | KDM4EALDH1A1TSHR | |
| SCHEMBL7401869 | 0.71 | KDM4E (0.38) | KDM4EALDH1A1TSHR | |
| SCHEMBL7393970 | 0.71 | KDM4E (0.38) | KDM4EALDH1A1TSHR | |
| SCHEMBL27572710 | 0.71 | KDM4E (0.44) | KDM4EALDH1A1TSHR | |
| SCHEMBL11354719 | 0.70 | KDM4E (0.42) | KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307837-A2 | Renin-inhibiting peptidyl heterocycles | ABBOTT LABORATORIES (US) | 1989-03-22 | — | — | EP | disclosed |