Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM4B | O94953 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7393970 | 1.00 | KDM4E (0.38) | KDM4EKDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL16287666 | 0.83 | KDM4E (0.40) | KDM4EKDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL28358210 | 0.83 | KDM4E (0.40) | KDM4EKDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL7297273 | 0.81 | USP30 (0.37) | KDM4E | |
| SCHEMBL7443725 | 0.76 | ALDH1A1 (0.39) | ALDH1A1TSHR | |
| SCHEMBL6209579 | 0.73 | CPA3 (0.47) | ALDH1A1 | |
| SCHEMBL6209574 | 0.73 | CPA3 (0.47) | ALDH1A1 | |
| SCHEMBL28517018 | 0.73 | KDM4E (0.39) | KDM4EKDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL11354719 | 0.72 | KDM4E (0.42) | KDM4EKDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL3161028 | 0.71 | KDM4E (0.41) | KDM4EKDM4AKDM4BKDM5CKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992000972-A1 | RENIN INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1992-01-23 | — | — | WO | disclosed |