Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.60 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 7/20 | 0.56 |
| ▸ | MGLL | Q99685 | 1/20 | 0.56 |
| ▸ | GUSB | P08236 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 5/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8880568 | 0.84 | LTA4H (0.64) | BCHEMGLLGUSBMAOB | |
| SCHEMBL8042202 | 0.81 | MAOB (0.58) | CYP4F2CYP4A11BCHEGUSBMAOB | |
| SCHEMBL1636426 | 0.81 | BCHE (0.58) | CYP4F2CYP4A11BCHEGUSBMAOB | |
| SCHEMBL8928219 | 0.80 | CHRM2 (0.58) | — | |
| SCHEMBL2206195 | 0.80 | CYP4F2 (0.66) | CYP4F2CYP4A11BCHEMGLLMAOB | |
| SCHEMBL19281462 | 0.80 | CYP4F2 (0.66) | CYP4F2CYP4A11BCHEMGLLMAOB | |
| SCHEMBL3169044 | 0.80 | CYP4F2 (0.66) | CYP4F2CYP4A11BCHEMGLLMAOB | |
| SCHEMBL4568936 | 0.80 | CYP4F2 (0.66) | CYP4F2CYP4A11BCHEMGLLMAOB | |
| SCHEMBL16493762 | 0.80 | CYP4F2 (0.66) | CYP4F2CYP4A11BCHEMGLLMAOB | |
| SCHEMBL3165628 | 0.80 | CYP4F2 (0.81) | CYP4F2CYP4A11BCHEMGLLMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |