Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30648612 | 0.84 | GLO1 (0.58) | GLO1KMT2AALDH1A1MEN1LMNA | |
| SCHEMBL7483326 | 0.84 | GLO1 (0.64) | GLO1KMT2AALDH1A1MEN1LMNA | |
| SCHEMBL7279772 | 0.84 | GLO1 (0.64) | GLO1KMT2AALDH1A1MEN1LMNA | |
| SCHEMBL18832135 | 0.81 | GLO1 (0.54) | GLO1KMT2AALDH1A1MEN1LMNA | |
| SCHEMBL7272467 | 0.81 | GLO1 (0.68) | GLO1KMT2AALDH1A1MEN1LMNA | |
| SCHEMBL10690139 | 0.81 | GLO1 (0.68) | GLO1KMT2AALDH1A1MEN1LMNA | |
| SCHEMBL10690145 | 0.81 | GLO1 (0.68) | GLO1KMT2AALDH1A1MEN1LMNA | |
| SCHEMBL6177870 | 0.81 | GLO1 (0.74) | GLO1KMT2AMEN1LMNAFBP1 | |
| SCHEMBL28015568 | 0.79 | GLO1 (0.57) | GLO1KMT2AALDH1A1MEN1LMNA | |
| SCHEMBL9727518 | 0.79 | GLO1 (0.64) | GLO1KMT2AALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1042727-C | Preparing for 2-acetoacetic ester | XINHUA PHARMACEUTIC FACTORY SH (CN) | 1999-03-31 | — | — | CN | disclosed |
| CN-1080631-A | 2-(oil of mirbane methylene radical) acetylacetic ester method for making | SHANDONG XINHUA PHARMACEUTIC F (CN) | 1994-01-12 | — | — | CN | disclosed |
| EP-0114273-B1 | NEW PHARMACOLOGICALLY ACTIVE PYRAZOLOPYRIDINES | GRUPPO LEPETIT S.p.A. (IT) | 1991-11-06 | — | — | EP | disclosed |
| US-4954508-A | HYPOTENSIVE | GRUPPO LEPETIT S.P.A. (IT) | 1990-09-04 | — | — | US | disclosed |
| EP-0114273-A1 | New pharmacologically active pyrazolopyridines | GRUPPO LEPETIT S.p.A. (IT) | 1984-08-01 | — | — | EP | disclosed |