Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288603 | 0.89 | KMT2A (0.41) | — | |
| SCHEMBL7288053 | 0.85 | REN (0.48) | REN | |
| SCHEMBL7281087 | 0.85 | REN (0.47) | REN | |
| SCHEMBL7279027 | 0.84 | REN (0.44) | REN | |
| SCHEMBL7278564 | 0.84 | REN (0.44) | REN | |
| SCHEMBL7288675 | 0.79 | REN (0.55) | REN | |
| SCHEMBL7281639 | 0.77 | REN (0.45) | REN | |
| SCHEMBL7281155 | 0.77 | REN (0.45) | REN | |
| SCHEMBL7279482 | 0.77 | REN (0.47) | REN | |
| SCHEMBL7278750 | 0.77 | CYP2C19 (0.36) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589446-B1 | N-(Hydroxyethyl)butanediamide derivatives as renin inhibitors | BOEHRINGER INGELHEIM CA LTD (CA) | 1997-09-03 | — | — | EP | claimed |