Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.67 |
| ▸ | ITGA2B | P08514 | 18/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.50 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.50 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8881759 | 0.89 | SMN1; SMN2 (0.55) | ITGB3ITGA2BSMN1; SMN2 | |
| Iodide SCHEMBL8882822 | 0.86 | ITGB3 (0.53) | ITGB3ITGA2BSMN1; SMN2 | |
| SCHEMBL8770567 | 0.84 | ITGB3 (0.70) | ITGB3ITGA2BF2PLGPRSS1 | |
| SCHEMBL7276548 | 0.84 | ITGB3 (0.70) | ITGB3ITGA2BF2PLGPRSS1 | |
| SCHEMBL8880311 | 0.83 | ITGB3 (0.48) | ITGB3ITGA2BSMN1; SMN2 | |
| SCHEMBL7291775 | 0.82 | ITGB3 (0.61) | ITGB3ITGA2BSMN1; SMN2F2PLG | |
| SCHEMBL8689949 | 0.81 | ITGB3 (0.66) | ITGB3ITGA2BSMN1; SMN2F2PLG | |
| SCHEMBL8382567 | 0.81 | ITGB3 (0.60) | ITGB3ITGA2BF2PLGPRSS1 | |
| Ro-44-3888 SCHEMBL7284509 | 0.81 | ITGB3 (1.00) | ITGB3ITGA2B | |
| Ro-44-3888 SCHEMBL7283142 | 0.81 | ITGB3 (1.00) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658928-A | ANTICOAGULANTS, ANTIINFLAMMATORY AGENTS, ANTITUMOR AGENTS,WOUND HEALING AGENTS, OSTEOPOROSIS | HOFFMANN-LA ROCHE INC. (US) | 1997-08-19 | — | — | US | disclosed |
| US-5545658-A | FOR TREATMENT OR PROPHYLAXIS OF ILLNESSES WHICH ARE CAUSED BY THE BINDING OF ADHESIVE PROTEINS TO BLOOD PLATELETS AND BY BLOOD PLATELET AGGREGATION AND CELL-CELL ADHESION | HOFFMAN-LA ROCHE INC. (US) | 1996-08-13 | — | — | US | disclosed |
| US-5378712-A | Antithrombosis | Hoffmann-La Roche Inc (US) | 1995-01-03 | — | — | US | disclosed |
| EP-0505868-A2 | N-Acyl-alpha-aminoacids derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-09-30 | — | — | EP | disclosed |