Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.70 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.70 |
| ▸ | TPSAB1 | Q15661 | 6/20 | 0.49 |
| ▸ | F2 | P00734 | 3/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.49 |
| ▸ | TPSD1 | Q9BZJ3 | 3/20 | 0.49 |
| ▸ | TPSG1 | Q9NRR2 | 3/20 | 0.49 |
| ▸ | PLG | P00747 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770179 | 0.86 | ITGB3 (0.74) | ITGB3ITGA2BTPSAB1F2PRSS1 | |
| SCHEMBL7282873 | 0.84 | ITGB3 (0.67) | ITGB3ITGA2BTPSAB1F2PRSS1 | |
| SCHEMBL8770297 | 0.84 | ITGB3 (0.53) | ITGB3ITGA2BTPSAB1F2PRSS1 | |
| Ro-44-3888 SCHEMBL7284509 | 0.82 | ITGB3 (1.00) | ITGB3ITGA2B | |
| Ro-44-3888 SCHEMBL7283142 | 0.82 | ITGB3 (1.00) | ITGB3ITGA2B | |
| SCHEMBL7276540 | 0.81 | ITGB3 (0.77) | ITGB3ITGA2B | |
| SCHEMBL7276548 | 0.81 | ITGB3 (0.70) | ITGB3ITGA2BTPSAB1F2PRSS1 | |
| SCHEMBL7283177 | 0.81 | ITGB3 (0.77) | ITGB3ITGA2B | |
| SCHEMBL7294041 | 0.81 | ITGB3 (0.78) | ITGB3ITGA2B | |
| SCHEMBL7284294 | 0.81 | ITGB3 (0.81) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632019-B1 | Acylureas | ZENECA LTD (GB) | 1997-09-24 | — | — | EP | claimed |
| US-5576334-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1996-11-19 | — | — | US | claimed |
| EP-0632019-A1 | Acylureas | ZENECA LIMITED (GB) | 1995-01-04 | — | — | EP | claimed |
| EP-0632019-B1 | Acylureas | ZENECA LTD (GB) | 1997-09-24 | — | — | EP | disclosed |
| US-5576334-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1996-11-19 | — | — | US | disclosed |
| EP-0632019-A1 | Acylureas | ZENECA LIMITED (GB) | 1995-01-04 | — | — | EP | disclosed |