Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PPIA | P62937 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780384 | 0.84 | HTR7 (0.58) | KDM4EALDH1A1HTR7ADRB2SMN1; SMN2 | |
| SCHEMBL28600060 | 0.77 | TDP1 (0.50) | MEN1KMT2AMAPK1L3MBTL1HTT | |
| SCHEMBL6539854 | 0.76 | HTT (0.45) | KDM4EALDH1A1SMN1; SMN2IDO1MAPK1 | |
| SCHEMBL19806810 | 0.75 | HTT (0.51) | KDM4EMEN1KMT2AIDO1LMNA | |
| SCHEMBL27459272 | 0.74 | HTR7 (0.51) | KDM4EALDH1A1HTR7ADRB2SMN1; SMN2 | |
| SCHEMBL3969795 | 0.74 | PTPRC (0.51) | ALDH1A1 | |
| SCHEMBL27540487 | 0.72 | SYK (0.48) | KDM4EALDH1A1HTR7ADRB2IDO1 | |
| SCHEMBL3068735 | 0.71 | TDP1 (0.56) | ALDH1A1SMN1; SMN2KMT2ATP53MAPK1 | |
| SCHEMBL31019371 | 0.71 | AR (0.46) | KDM4EALDH1A1HTR7ADRB2SMN1; SMN2 | |
| SCHEMBL28481944 | 0.71 | AR (0.46) | KDM4EALDH1A1HTR7ADRB2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644199-B1 | Cyclic antimicrobial peptides and preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-5693750-A | MICROBIOCIDAL ACTION AGAINST PNEUMOCYSTIS INFECTIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
| US-5569646-A | TREATMENT OF PNEUMONIA; MICROBIOCIDES, FUNGICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-29 | — | — | US | disclosed |
| EP-0644199-A1 | Cyclic antimicrobial peptides and preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |